About the Project
Focal Theology Area on Nanomedicines for Personalized Theranostics
Focal Technology Area (FTA) on Nanomedicines for Personalized Theranostics is a consortium of 11 research laboratories at several universities that will develop nanometer-sized drug delivery systems for theranostics (therapy and diagnostics) of angiogenesis-dependent diseases such as cancer, inflammation and cardiovascular diseases in a personalized manner. The Israel National Nanotechnology Initiative (INNI) is responsible for the project, which is led by Prof. Dan Peer, of the Department of Cell Research and Immunology at Tel Aviv University.
Advances in nano-scale science and bio-nano-engineering are revolutionizing our understanding and ability to manipulate complex biological processes, as well as the way health care is administered. These approaches and innovations, collectively termed as Nanomedicine, are on the verge of improving disease prevention, detection, treatment and management.
The development of nanomedicines for theranostics of diseases is driven by principles from diverse fields of science. Unlike conventional therapies, targeted nanomedicines have the potential to offer more effective treatment with significantly reduced adverse effects through specific interactions with cells. Additionally, they allow for; (i) enhanced specificity in the delivery of large amounts of therapeutic or imaging payloads per recognition event; (ii) the capacity to deliver multiple agents simultaneously, and ;(iii) the incorporation of mechanisms to overcome biological barriers and drug resistance.
Uncovering new molecular targets involved in the switch to progressive disease could provide important tools for novel selective therapy strategies. This approach will enable the design, synthesis and characterization of “magic-bullet”-like Nanomedicines for Personalized Theranostics allowing specific targeting of drugs, leading to significantly safer and more effective therapies.
The director of the FTA:
Prof. Dan Peer, Ph.D
Head of the laboratory of Nanomedicine
at Tel Aviv University (TAU).
Department of Cell Research and Immunology
Tel Aviv University
Tel Aviv 69978, Israel
Office phone: 972-3-6405926
Lab phone: 972-3-6407925
Office fax: 972-3-6405926
Home page: www.tau.ac.il/~peer