Carbon nanotube based multi electrode arrays

In the last several years we have developed a novel class of micro electrodes for neuronal recording and stimulation. The electrodes are fabricated by synthesizing high density carbon nanotube islands on lithographically defined, passivated titanium nitride conductors on a silicon dioxide substrate.  
 
Recently, we have also developed a flexible version of these electrodes. The enhanced electrochemical properties of the electrodes, their flexible and simple micro-fabrication preparation procedure as well as their bio-compatibility and durability suggest that carbon nanotube electrodes are a promising platform for high resolution neuronal coupling. These electrodes are currently explored primarily for surface EMG and EEG applications.
 
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One to one neuron-electrode interfacing
Alon Greenbaum, Sarit Anava, Amir Ayali, Mark Shein, Moshe David-Pur, Eshel Ben-Jacob and Yael Hanein
Journal of Neuroscience methods, 2009.
 
Carbon nanotube electrodes for effective interfacing with retinal tissue
Asaf Shoval, Christopher Adams, Moshe David-Pur, Mark Shein, Yael Hanein and Evelyne Sernagor, Frontiers in NeuroEngineering, 2009, Full text: html
 
All-carbon-nanotube flexible neuronal electrodes 
Moshe David-Pur, Mark Shein, Lilach Bareket, Giora Beit-Ya’akov, Nizan Herzog, Yael Hanein,
Biomed Microdevices, DOI 10.1007/s10544-013-9804-6, 2013. Full Text: Link.

Contact Details

Admin: Ms. Sara Ben Arie (This email address is being protected from spambots. You need JavaScript enabled to view it.)

Mail address: Prof. Yael Hanein (This email address is being protected from spambots. You need JavaScript enabled to view it.), School of Electrical Engineering, Tel-Aviv University, Ramat-Aviv, Tel-Aviv, 69978, Israel. 

Office address: (1) EE Building (Map), Office 232 and (2) Center for Nanoscience and Nanotechnology (Map), Office 003.

Labs: (1) EE building, Room: 207, 972-3-6407937, and (2) Center for Nanoscience and Nanotechnology, Rooms: 05, 06, 07, 08, 20, 972-3-6405707, 5709, 8379.

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Flexible micro electrodes

We are using carbon nanotube technology to develop superior flexible electrodes for neuronal interfacing. These electrodes alllow not only simple fabrication scheme but also offer high durability, low stimulation threshold and simple integration with other advanced technologies. 

Engineered Neural Circuits

Engineered neural networks are used to investigate the interplay between function and form in neuronal systems.

Neuronal Mechanics

Locust neurons are used to explore mechancial effects affecting neuronal development. We use micro suspended beams and carbon nanotube islands, to monitor the cells.

NanoRectenna

Nanorectennae: A new approach to rectify solar energy.

Carbon Nanotube Neural Interfaces

We are using nanotechnology, in particular carbon nanotube technology, to build interfaces for neuronal system. We use these inetrfaces both for basic investigations as well as to develop new electrodes for future neural implants. 

Mapping Neuronal Recording and Stimulation

Combined MEA and Ca recordings is used to explore to better understand micro neuronal recording and stimulations.

Neuronal Entanglement

Neurons appear to favor rough surfaces. The underlying mechanisms is not well understood and we are trying using various approaches to explore this effect. Using confocal flourescent imaging we were able to show how neurons and glia cells bind to three dimensional carbon nanotubes suggesting that neurons have an innate tendency to interwine into three dimensional support. 

Yael Hanein, Ph.D. School of Electrical Engineering; Physical Electronics, Tel Aviv University, Tel Aviv 69978, Israel. Phone: +972-3-6407698 Fax: +972-3-6423508