Protein and peptide-based molecular nanomaterials for biomedical applications.
Biological systems use a precise control in space and time to form functional materials, however, their dynamic properties are not yet accessible in man-made biomaterials. Our vision is to fill this gap by studying the manufacturing process of biological materials used in nature and applying these insights into design tools for biomaterials.
- Compartmentalization of enzymatic reactions in synthetic organelles;
- Molecular self-assembly of ordered/disordered peptide and protein structures and their biophysical characterization;
- Design rules of peptide assemblies as models for membraneless organelles;
- Design of dynamic bioreactors formed by multicomponent peptide-based building blocks;